It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. How much does plaquenil cost Plaquenil antinflammatory Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some. It is a known adverse reaction to quinine; hydroxychloroquine, as a synthetic derivative of this parent compound, may also put patients at risk of this complication. However, reports of hydroxychloroquine‐induced TTP are extremely rare in the literature. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Plaquenil induced rash Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus., Suspected hydroxychloroquine‐induced thrombotic thrombocytopaenic. Can you take plaquenil and synthroidItchy palms plaquenil SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hydroxychloroquine Plaquenil. Itching From Plaquenil DailyStrength. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. But I don't know if such a rash would itch; your dr. is your best source on what a Plaquenil-induced rash might look & feel like. Most lupus rashes tend NOT to itch, per most mainstream sources. The main exception is hives, which people with lupus ARE more prone to getting, I've read. Cutaneous adverse reactions to hydroxychloroquine have been described, including acute generalized exanthematous pustulosis 11, 12, Stevens-Johnson syndrome 13, and toxic epidermal necrolysis 14–16. Here we report a case of hydroxychloroquine-induced erythema multiforme after 12 days of exposure in a 25 year old woman with lupus.