Those with APS make abnormal proteins called antiphospholipid autoantibodies in the blood. This causes blood to flow improperly and can lead to dangerous clotting in arteries and veins, problems for a developing fetus and pregnancy miscarriage. What is the best time of day to take hydroxychloroquine Test for plaquenil retinopathy The goals of treatment in pregnant women with antiphospholipid syndrome are to improve maternal and fetal- neonatal outcomes by keeping to a minimum the risks of the recognised complications of the disorder, including maternal thrombosis, fetal loss, preeclampsia, placental insufficiency, and fetal growth restriction, and the need for iatrogenic preterm birth. Antiphospholipid syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Neurontin, and have Osteoporosis An equal, if not more important risk is the risk of preterm birth. Preterm birth in lupus is usually not due to antiphospholipid antibodies, but due to pre-eclampsia and premature rupture of membranes. Risk factors for preterm birth in general include active lupus, high dose prednisone, and renal disease. APS affects women five times more commonly than men. People with this disorder may otherwise be healthy, or they also may suffer from an underlying disease, most frequently systemic lupus erythematosus (commonly called lupus or SLE). Plaquenil preeclempsis antiphospholipid Antiphospholipid syndrome - Symptoms and causes - Mayo Clinic, Will you have Antiphospholipid syndrome with Plaquenil. Plaquenil which companyRa med hydroxychloroquine Antiphospholipid syndrome is defined by the combination of thrombotic events and/or obstetric morbidity in patients who have tested positive persistently for antiphospholipid antibodies. With good treatment, approximately 70% of pregnant women with antiphospholipid syndrome will deliver a viable live infant. The impact of hydroxychloroquine treatment on pregnancy.. Lupus and Pregnancy Johns Hopkins Lupus Center. Antiphospholipid Syndrome -. Antiphospholipid Syndrome. As if receiving a diagnosis of lupus is not complicated and scary enough, being diagnosed with something called antiphospholipid pronounced An-ti-fos-fo-LIP-id syndrome APS can be even more scary and confusing. Pregnant women with antiphospholipid antibodies as well as their babies should always be monitored. Throughout the pregnancy, ultrasounds can track the placenta and its blood flow to assure the baby is healthy. Towards the end of pregnancy, blood pressure should be frequently monitored in case of preeclampsia. Plaquenil Benefits Pregnant Women with Anti-Phospholipid Syndrome. reports that pregnant women with APL antibodies and who took Plaquenil HCQ or hydroxychloroquine had better pregnancy outcomes than those who did not. This study compared Group A - 31 women 51 pregnancies on HCQ.