Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Amaurosis fugax from plaquenil Anesthetic considerations for patients on plaquenil Aug 14, 2017 Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects. diarrhea. dizziness. hair loss. headache. increased skin sensitivity to sunlight. loss of appetite. Plaquenil and Vaginal bleeding between periods - from FDA reports Summary Vaginal bleeding between periods is found among people who take Plaquenil, especially for people who are 30-39 old, have been taking the drug for 1 - 2 years, also take medication Methotrexate, and have Nausea. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil side effects bleeding Plaquenil Hydroxychloroquine - Side Effects, Dosage., Plaquenil - Uses, Side Effects, Interactions - Hydroxychloroquine nclexChloroquine uk pharmacyPlaquenil for autoimmune disordersIs hydroxychloroquine the same as plaquenilHow long does plaquenil take to work for hives Plaquenil side effects Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Plaquenil Uses, Dosage & Side Effects -. Will you have Vaginal bleeding between periods with Plaquenil.. Plaquenil Oral Uses, Side Effects, Interactions.. Heavy or prolong menstrual bleeding is found among people who take Plaquenil, especially for people who are 40-49 old, have been taking the drug for 5 - 10 years, also take medication Humira, and have Osteoporosis These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or. Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss.