Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Does plaquenil cause low wbc Chloroquine antibacterial activity Pka of chloroquine Hypoglycemia Plaquenil has been shown to cause severe hypoglycemia including loss of consciousness that could be life threatening in patients treated with or without antidiabetic medications see DRUG INTERACTIONS and ADVERSE REACTIONS. Patients treated with Plaquenil should be warned about the risk of hypoglycemia and the associated clinical signs and symptoms. Plaquenil and hypoglycemia? Has anyone experienced this side effect? Newly diagnosed with early RA, rheumatologist started me on 200mg Plaquenil 1x/day for first two weeks, going up to 2x/day after two weeks. She told me it's very safe and generally well tolerated. Then about a week after going up to the full dosage I woke up feeling shaky. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and hypoglycemia Hydroxychloroquine and hypoglycaemia Most people., Plaquenil and hypoglycemia? rheumatoid Hydroxychloroquine porphyria cutanea tarda Suicidal behavior has been rarely reported in patients treated with PLAQUENIL. Hypoglycemia. PLAQUENIL has been shown to cause severe hypoglycemia including loss of consciousness that could be life threatening in patients treated with or without antidiabetic medications see DRUG INTERACTIONS and ADVERSE REACTIONS. Patients treated with. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. The effect of hydroxychloroquine on glucose control and.. Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. I feel shaky, weak, dizzy, nauseous, etc. if I take Plaquenil on an empty stomach. I take it after dinner when stomach is full and with fatty food healthy fats like avocado, nuts, or small piece of low fat cheese. I can't take Plaquenil during the day due to its side effects so taking it at dinner lets me sleep away the side effects like. Plaquenil and Hypoglycemia Yesterday I was cruising around on the Sjogren's World Forum and came across an interesting topic of discussion. One of the sjoggies there who is diabetic noted that her blood sugars were consistently lower after she began taking Plaquenil hydroxychloroquine.