Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Side effects with plaquenil Side effects of hydroxychloroquine and mycophenolate Dose of chloroquine to inhibit autophagy Jul 08, 2019 Pharmacokinetics Following a single 200 mg oral dose of hydroxychloroquine sulfate tablets to healthy male volunteers, the mean peak blood concentration of hydroxychloroquine was 129.6 ng/mL, reached in 3.26 hours with a half-life of 537 hours 22.4 days. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Dosage forms Variable daily dosing eg, alternating or skipping doses on certain days each week may be used to obtain the recommended dose for rheumatologic uses. All doses below are expressed as hydroxychloroquine sulfate salt. Hydroxychloroquine sulfate salt 200 mg is equivalent to hydroxychloroquine base 155 mg. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine sulphate dosage PLAQUENIL® HYDROXYCHLOROQUINE SULFATE TABLETS, USP, Hydroxychloroquine Side Effects, Dosage, Uses, and More Hydroxychloroquine in lupus pregnancyHerpes and plaquenilPlaquenil kidney pain Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Hydroxychloroquine Professional Patient Advice -. Hydroxychloroquine - Side Effects, Dosage, Interactions.. In a small percentage of patients, side effects may require temporary reduction of the initial dosage. Maintenance adult dosage When a good response is obtained, the dosage may be reduced by 50 percent and continued at a maintenance level of 200 mg to 400 mg 155 to 310 mg base daily, administered as a single daily dose or in two divided doses. Hydroxychloroquine is a relatively well tolerated medicine. The most common adverse reactions. reported are stomach pain, nausea, vomiting, and headache. These side effects can often be lessened by taking hydroxychloroquine with food. Hydroxychloroquine may also cause itching in some people. All medicines may have some side effects. One of the most serious side effects is a toxicity in the eye generally with chronic use. People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams.