Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Natural substitute for plaquenil Why does hydroxychloroquine cost so much Is plaquenil an immunosuppressant drug Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Side effects In some people, HCQ may cause gastrointestinal problems, such as nausea, vomiting, upset stomach, cramps, or diarrhea. These may occur for the first few days a person takes the drug while the body adjusts to the medication. Loss of appetite, tiredness, weakness, or headache are uncommon side effects and typically go away over time. Many people using this medication do not have serious side your doctor immediately if any of these unlikely but serious side effects occur arm/leg/back pain, fast heartbeat, hair loss/color change, mental/mood changes e.g. anxiety, depression, hallucinations, ringing in the ears/hearing loss, worsening of skin conditions e.g. psoriasismedication may infrequently cause serious sometimes permanent eye problems or muscle damage, especially if you take it for a long time. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine lupus side effects Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus., Drug spotlight on hydroxychloroquine Lupus Foundation of. Treated with primaquine and chloroquine Hydroxychloroquine Side Effects. When treating lupus or arthritis, hydroxychloroquine is usually given daily for several weeks or months. For best results, keep using the medication as. Hydroxychloroquine - Side Effects, Dosage, Interactions.. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical.. Plaquenil Side Effects Common, Severe, Long Term -. Call your doctor right away if you notice any of these side effects Blurred vision or changes in your vision Convulsions, seizures, or other neurological symptoms these are very rare Muscle aches or weakness HYDROXYCHLOROQUINE is used to treat rheumatoid arthritis and systemic lupus erythematosus. It is also used to treat malaria. The lowest GoodRx price for the most common version of generic Plaquenil is around $18.60, 90% off the average retail price of $196.17. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine.