Fortunately, it was discovered these drugs often are helpful in the treatment of various rheumatic diseases, particularly systemic lupus erythematosus (SLE or "Lupus") and rheumatoid arthritis. Although chloroquine is sometimes used, the preferred antimalarial drug is hydroxychloroquine due to its greater safety. It is not possible at the present time to explain precisely why hydroxychloroquine is effective in various rheumatic diseases. Hydroxychloroquine fatigue Plaquenil sun pharmaceuticals Chloroquine mechanism mitochondria Drug hydroxychloroquine oral-tablet 200mg Chloroquine and hydroxychloroquine. Chemical formula of hydroxychloroquine sulfate commonly known by its old brand-name Plaquenil were first used to treat malaria, but the malaria-causing organism soon became resistant to them. However, during the treatment of patients with malaria who also had lupus, it was noted that their skin rashes improved. That's a real common side effect of Lupus is unexplained rashes. If you've ever had an allergic reaction to a drug then this is the type of reaction you'd have if you were allergic to the Plaquenil; and they'd stay until the Plaquenil was out of your system. If they're coming and going more than likely it isn't the Plaquenil. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Hydroxychloroquine is a tablet that is best taken with food as it has a slightly bitter taste. When effective, it can decrease damage to the tissues of the joints, skin and other organs in the body. Does plaquenil cure lupus Hydroxychloroquine Plaquenil Side Effects & Dosage for., Plaqunil rash - Chloroquine nurses responsibilityPlaquenil effects on diarrheaPlaquenil and age spotsPlaquenil for sle Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. RA and Hydroxychloroquine How Effective is it for.. Plaquenil is sold in 200mg tablets. The recommended adult dosage for a person with lupus is 200 to 400 mg daily. It can be taken in two doses or at one time. Doses above 400 mg/day are not recommended. Today’s AMs are hydroxychloroquine Plaquenil®, chloroquine Aralen®, and quinacrine Atabrine®. Quinacrine is no longer marketed in the U. S.; it can be dispensed by a compounding pharmacy, although insurance companies may not pay for it. The antimalarial quinine was first used to treat cutaneous lupus in 1834. Therefore, there is not an absolute contraindication to using sulfa or sulfonamide medications in those with lupus. Treatment is individualized. lfa Does Plaquenil cause hair loss, thinning or drying out? I have been losing a great deal of hair recently.