Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Usp grade chloroquine Hydroxychloroquine vs doxycycline Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Oral mouth and nasal nose ulcers are one of the most common features of lupus occurring in around 45% of people who have SLE. Having mucosal ulcers in the mouth or nose is one of the classification criteria used to diagnose SLE. Plaquenil is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil for ulcers Stomach problems with Plaquenil • Johns Hopkins Arthritis Center, Coping with Oral and Nasal Ulcers in Lupus - LUPUS UK Plaquenil skin cha ges Mouth ulcers is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months, also take medication Enbrel, and have Osteoporosis. Will you have Mouth ulcers with Plaquenil - eHealthMe. Plaquenil Uses, Dosage & Side Effects -. Adverse drug events in the oral cavity - ScienceDirect. Hydroxychloroquine received an overall rating of 7 out of 10 stars from 368 reviews. See what others have said about Hydroxychloroquine, including the effectiveness, ease of use and side effects. Children—Use and dose must be determined by your doctor. For treatment of lupus Adults—200 to 400 milligrams mg taken as a single dose or in two divided doses once a day. However, dose is usually not more than 400 mg once a day. Children—Use and dose must be determined by your doctor. Summary Gastric ulcer is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take medication Enbrel, and have Pain.