Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Withdrawal from hydroxychloroquine Actavis pharma plaquenil In addition, any of the regimens listed above for the treatment of chloroquine-resistant malaria may be used for the treatment of P. malariae and P. knowlesi infections. P. vivax and P. ovale Quinine remains an important and effective treatment for malaria today, despite sporadic observations of quinine resistance. 1 Chloroquine. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin chloroquine and Sontochin 3-methyl-chloroquine. Resistance to anti-malarials is a major challenge for effective malaria control in sub-Saharan Africa. This triggered a need for routine monitoring of the efficacy of the antimalarial drugs every two years in all malaria endemic countries. Chloroquine remained the drug of choice for the treatment of vivax malaria in Ethiopia. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. The mainstay of treatment for malaria is chloroquine Medicines for the Prevention of Malaria While Traveling., History of antimalarials Medicines for Malaria Venture Benefits of hydroxychloroquinePlaquenil skin rash side effectsPlaquenil wikiPlaquenil toxicity and eyesTumors associated with plaquenil For treatment of acute attacks of malaria in adults, one dose is usually taken right away, followed by half the dose 6 to 8 hours later and then half the dose once a day for the next 2 days. For prevention and treatment of malaria in infants and children, the amount of chloroquine phosphate is based on the child's weight. Chloroquine MedlinePlus Drug Information. Efficacy of Chloroquine for the Treatment of Vivax malaria.. Improving adherence to malaria treatment for children the.. Covid-19 the anti-malaria chloroquine, a very preliminary track to be taken with caution Paris AFP A treatment for malaria, chloroquine, has shown signs of effectiveness against the new coronavirus, according to a preliminary study carried out in China, but several experts call for caution in the absence of further studies and because of its side effects which can be serious. Chloroquine CQ has remained the first-line of treatment for P. vivax since the 1940s 2 and seemed to be universally effective until the first case of CQ-resistant P. vivax was reported from Papua New Guinea 3. There have been some reports of CQ resistance across the globe 4 but CQ remains the mainstay of treatment in most regions. Chloroquine can be used to kill malaria parasites living in red blood cells but the medication may not necessarily be efficient at killing these parasites in other body tissues. Doctors often prescribe this medication as part of certain treatment plans for lupus and other immune system diseases.