These drugs are called disease-modifying antirheumatic drugs (DMARDs), and they are an important part of an overall treatment plan. Disease-modifying drugs act on the immune system to slow the progression of rheumatoid arthritis. This is why they are called "disease-modifying." Many different drugs can be used as DMARDs in the treatment of RA, but some are used more often than others. Plaquenil and laser hair removal Chloroquine mode of action malaria Hi guys, I was diagnosed with RA in April 08 and I'm 29 years old. My doctor was only able to find it after I requested a MRI of my hands. He believed it was in the very early stages and not extremely bad so prescribed Plaquenil/Hydroxychloroquine since it is the RA drug with the least side. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Dosage While in some cases, lower doses of NSAIDS are effective, in rheumatoid arthritis and other forms of inflammatory arthritis a higher dose is often required to decrease inflammation. A lower dosage can initially be used if inflammation is mild, if mechanical pain is the major problem. They are not as powerful as other DMARDs, but they usually cause fewer side effects. Hydroxychloroquine (Plaquenil) and sulfasalazine (Azulfidine) are used for mild rheumatoid arthritis. Plaquenil and prednisone for rheumatoid arthritis Hydroxychloroquine Side Effects, Dosage, Uses, and More, Hydroxychloroquine Plaquenil Where to buy chloroquine phosphateHydroxychloroquine mechanism of action medscapeIs there a generic form of plaquenilNosebleed plaquenil Although Plaquenil is an older drug, it is still available and prescribed to some people who have rheumatoid arthritis or certain other rheumatic diseases. Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. Taking Plaquenil for Rheumatoid Arthritis. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Plaquenil, prednisone DailyStrength. What Conditions Does This Treat? Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. Aug 22, 2008 Plaq is not a substitute for prednisone. Prednisone is an intermediate acting corticosteroid-which means it has direct anti-inflamitory properties that take effect begining in a few hours. It is ment to get this undercontrol now and diminish your pain. Plaq is a longer time medication it may take two months before their is a noticable difference. I have had RA for 10 years and have been on Plaquenil pretty much the whole time. Methotrexate did not work for me and made me very nauseous. I also take 5-10 mg prednisone and an injection of Humira every week. I have had no side effects from the Plaquenil. Prednisone is a mean drug however, I can tell you this as a nurse too but I have to.