It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Benefits of hydroxychloroquine Plaquenil eye toxicity I was even thinking of trying it again to see if the rash was just a one-off thing, but after doing some research I found a study about patients' allergic reactions to Plaquenil and the pictures looked exactly like my rash. Also read that allergic reactions can get even worse when triggered again, so I won't be trying anymore. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. For example Plaquenil Your body then makes a chemical that causes the allergic reaction. So every time you are exposed to the allergan, the body makes the chemical very quickly as it now knows how and you get a rash, or other symptoms. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil allergic reaction rash Rash 22 Common Skin Rashes, Pictures, Causes, and Treatment, Hydroxychloroquine Side Effects Common, Severe, Long Term. Can you take tramadol with hydroxychloroquineChloroquine and primaquine treatmentHydroxychloroquine sulfate tablets usp 200 mg side effects I got this after about 5 weeks, mine was a blistery rash and it was only on my shoulders, upper chest and upper back. My doctor said it was photodermatitis and caused from a sensitivity to the sun caused by the plaquenil. Rash from plaquenil DailyStrength. Allergic reaction to plaquenil DailyStrength. Hydroxychloroquine DermNet NZ. Plaquenil allergic reaction -rash. What now? Hello everyone! I hit the three week mark for taking my meds of Plaquenil and Medrol & 2 days ago I got itchy red marks that became bumpy when I scratched them. I've never had the lupus rash, and this is not from sun or heat. I live in Florida, I never go outside - that and it's been raining for days. Oh shoot! That is the pits. Nine chances out of 10 it will be an allergic reaction to the drug. And, yes, you can have a very isolated rash from a drug reaction. I had a 6-8 cm red wheal above my right knee with my allergic reaction to rifampin. It showed up about 6 weeks after I started the TB drugs for my M. kanasis. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness.