It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Black cohosh and plaquenil Can i take plaquenil if allergic to sulfa What does plaquenil do to eyes Background/Purpose The combination of methotrexate MTX, sulfasalazine SSZ and hydroxychloroquine HCQ triple therapy is a highly effective and well-tolerated treatment in rheumatoid arthritis RA. While MTX is the cornerstone of most successful combination therapies, not all patients are candidates for, or tolerate, MTX. Leflunomide, a disease-modifying anti-rheumatic drug DMARD. Drug interactions are reported among people who take Arava and Plaquenil together. This study is created by eHealthMe based on reports of 7,800 people who take Arava and Plaquenil from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. Leflunomide can commonly cause a mild rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe allergic reaction. Get. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Interactions with plaquenil and leflunomide Interactions among Low Dose of Methotrexate and Drugs Used in., Arava and Plaquenil drug interactions - eHealthMe Hydroxychloroquine aplastic anemia The doctor then kept me on my plaquenil and added Leflunomide Arava to replace the methotrexate. My mouth sores went away and I quit having the days of sickness from the methotrexate. There may be something better out there, but for me the Arava has made a big difference. Anyone used plaquenil and arava which is better? DailyStrength. Leflunomide Oral Uses, Side Effects, Interactions, Pictures.. Leflunomide Oral Interactions with Other Medication. Other Interactions. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. I have ra, am taking leflunomide 20 mg, prednisone 2.5 and plaquenil hydroxychloroquine 200 mg. I don't have in more I have ra, am taking leflunomide 20 mg, prednisone 2.5 and plaquenil hydroxychloroquine 200 mg. I don't have ins. Nov 01, 2018 CHICAGO – Combination therapy with leflunomide and hydroxychloroquine met all goals for efficacy, safety, and tolerability among patients with primary Sjögren’s syndrome in a randomized, placebo-controlled pilot study, lending support to evidence suggesting the two drugs have additive benefits.