Hydroxychloroquine induced cardiomyopathy and heart failure in twins

Discussion in 'Chloroquin' started by au121, 17-Mar-2020.

  1. Gladis8 Guest

    Hydroxychloroquine induced cardiomyopathy and heart failure in twins

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    Abstract. Chloroquine Hydroxychloroquine-induced cardiomyopathy is a rare but potentially life-threatening condition. Cessation of the culprit drug, along with aggressive afterload reduction therapy, has been associated with halting of disease progress and even improvement in patients' clinical and histologic status. We report HCQ-induced dilated cardiomyopathy in a woman with SS. Methods A 52 year old woman of Iraqi origin presented with a week’s history of dyspnoea at rest, palpitations, chest tightness, dry cough and peripheral oedema New York Heart Association class IV on a background of 3 months of progressive dyspnoea. Recently a Rapid Access. Genetic predisposition for HCQ‐induced cardiomyopathy was first proposed in a set of twin sisters who both suffered from SLE. 9 Chatre et al. described a case of a 61‐year‐old woman whose diagnosis of α‐galactosidase A deficiency was unmasked by chronic HCQ treatment. 10 Because Fabry disease and other lysosomal storage disorders, such.

    For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too.

    Hydroxychloroquine induced cardiomyopathy and heart failure in twins

    Hydroxychloroquine-induced restrictive cardiomyopathy a case., Hydroxychloroquine Induced Cardiotoxicity A Rare.

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    Hydroxychloroquine HCQ, a common anti-rheumatic medication, can be cardiotoxic and cause systolic or diastolic heart failure HF. A 65 year old man presented with acute decompensated HF. He had a history of rheumatoid arthritis, and had been treated with hydroxychloroquine for the last 8 years. Chloroquine CQ and hydroxychloroquine HCQ are anti‐rheumatic medications frequently used in the treatment of connective tissue disorders. We present the case of a 45‐year‐old woman with CQ‐induced cardiomyopathy leading to severe heart failure. On the basis of these classic findings, a diagnosis of hydroxychloroquine cardiomyopathy was made, and the drug was discontinued. Three months later her symptoms had completely resolved. Repeat imaging using cardiac magnetic resonance demonstrated an ejection fraction of 65% D, Online Video 2.

  4. FlyGuy XenForo Moderator

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  5. DenisG77 User

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  6. lifanova New Member

    Hydroxychloroquine and lichen planopilaris Efficacy and. Lichen planopilaris LPP and its variant frontal fibrosing alopecia FFA are primary lymphocytic cicatricial alopecias for which there is no evidence-based therapy. Objective We assessed the efficacy of hydroxychloroquine in active LPP and FFA using the LPP Activity Index LPPAI, a numeric score that allows quantification of the symptoms and signs of the condition for statistical comparison.

    Hydroxychloroquine Plaquenil for Cicatricial Alopecia.