It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Does hydroxychloroquine cause anxiety Side effects of stopping plaquenil Can hydroxychloroquine get you high Inform your doctor if your condition persists or worsens. It may take several weeks or months to see improvement if you are taking this for lupus or arthritis. Hydroxychloroquine may not prevent malaria in all cases. If you experience fever or other symptoms of illness, seek immediate medical attention. To treat malaria Plaquenil is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Generally, hydroxychloroquine is given in 200 mg or 400 mg doses, once per day. Higher doses can sometimes be used, but only in adults and not for all cases. Some people tolerate this medication much better than other people, so it is important that individuals who are considering taking hydroxychloroquine talk with their doctor about the lowest necessary dose to reduce or eliminate their symptoms. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Days plaquenil to work Plaquenil User Reviews for Rheumatoid Arthritis at, Plaquenil Uses, Dosage & Side Effects - Chloroquine scheduled drugPlaquenil hairlineStop antibodies drug plaquenilChloroquine retinopathy faAzathioprine and plaquenil Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. RA and Hydroxychloroquine How Effective is it for Rheumatoid.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. My question is for those that have taken Plaquenil/Hydroxychloroquine. How long did it take for it to remove symptoms in your personal experience? I know I've read it can take up to 6 months but what I'm wondering is, do you just wake up one day and find it's kicked in 6 months down the road or more likely, it starts to work slowly over 6 months? Hi - I just started Plaquenil 400 mg a day two week ago and I started feeling less achy and tired a few days ago. Is it possible for it to work quicker in some people? I've heard it can take months, but I must say that I haven't felt like this since I was a kid - not achy or stiff. Has anyone had a similar How long until Plaquenil started working? Support Forums. It's pretty suttle. One day all the sudden you will notice that your arms or legs or feet don't feel as bad as they used to. Not that it is a cure all but it usually does help. It kind of reminds me of a vitamin. You don't notice it's working until you stop taking it.