One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil and kidneys Plaquenil rheumatoid arthritis dosage A report in 2015 described that pericentral maculopathy without the classic parafoveal Bull's eye retinopathy is common in Asian 50% compared to Caucasian 2% patients, and Asian patients should, therefore, receive adapted screening tests such as a wider angle threshold visual field test. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. For radical cure of P. vivax and P. malariae infections, concomitant therapy with an 8-aminoquinoline compound is necessary. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Maculopathy plaquenil Hydroxychloroquine retinopathy A review of imaging, Retinal Physician - Hydroxychloroquine Maculopathy An. What blood tests are required while on plaquenilHydroxychloroquine bluelightChloroquine intercalating dnaSide effects of plaquenil on eyesEye screening for plaquenil The presence of bull’s-eye maculopathy indicates the disease has been progressing for years, resulting in foveal thinning and likely vision loss. 8 SD-OCT is a highly sensitive and reproducible imaging modality used in the detection of Plaquenil retinal toxicity. The preferential loss of photoreceptor IS/OS junction makes SD-OCT an ideal tool to identify early changes associated with Plaquenil retinal toxicity. How to Succeed in Plaquenil Screenings. Plaquenil Dosage Guide -. Hydroxychloroquine And Chloroquine Screening 2016 AAO.. Maculopathy, or macular degeneration, is a disease related to the central part of the retina, called macula. Maculopathy is characterized by a progressive loss of central vision, usually bilateral, that greatly impairs vision functions. Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders.