But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Read more Anxiety over potential eye problems with Hydroxychloroquine is completely unwarranted if the dose is kept below 6mg/kg (2.2lbs) of body weight. Read more See 1 more doctor answer It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Read more Results are very good, particulary when used alone and better with methotrexate. In regards to malaria what is chloroquine resistance Cost of plaquenil versus hydroxychloroquine Plaquenil eye report form Aug 02, 2018 Anti-rheumatic drug A medication first used for malaria, hydroxychloroquine Plaquenil® is used to treat rheumatoid arthritis, some lupus symptoms, childhood arthritis and other autoimmune diseases. NSAID painkillers Nonsteroidal Anti-Inflammatory Drugs are often used for joint pain, muscle aches, headaches and tenderness. NSAIDs can be. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects. Anybody would be with that diagnosis. But the drugs are safe. The side-effects are minimal. Not taking the drugs and pretending that there is a natural cure is dangerous. You need to understand that the drug was prescribed because it was proven effective in the treatment of lupus. There are side-effects with any drug, even natural ones. Chloroquine can be substituted for Plaquenil but only in limited circumstances. Please provide more detailed information if you want a more specific answer. Read more See 1 more doctor answer Depends on what you are being treated for.... Read more While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. So other meds like Imuran and Cell Cept (mycophenolate mofetil) also reduce flares, but also increases infection. Read more It depends why you are taking Plaquenil in the first place. Apart from some stomach quiziies, I have never stopped this drug, as long as it demonstrated it is working. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. Is there a natural drug substitute for plaquenil Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. How do i know if i'm allergic to hydroxychloroquineHydroxychloroquine sun allergyChloroquine injection intravenousPlaquenil lupus pregnancy Methotrexate Remove Methotrexate from your drug comparison. Celebrex celecoxib Remove Celebrex from your drug comparison. Prescribed for Lyme Disease - Arthritis, Dermatomyositis, Malaria, Malaria Prevention, Rheumatoid Arthritis, Systemic Lupus Erythematosus. May also be prescribed off label for Sjogren's Syndrome. Hydroxychloroquine Compared to Alternatives -. I am so afraid to take plaquenil for lupus treatment! any.. PLAQUENIL Patient Assistance Program. Glenn Frey's death, tied in part to rheumatoid arthritis medications he was taking, is a 'wake-up call' about the dangers of powerful drugs used to treat the condition, a top doc says. It should push arthritis patients and their doctors to seek out safer available alternatives. I'm still searching for that magic "all natural" replacement since I cannot tolerate plaquenil. The stomach, liver & eye complications are too great to bear. and that's at the lowest, lowest dose. Anyway, guess I need to get into some deeper research about exactly what this drug does, and see if there's an herb out there that may help. May 20, 2008 Because the action of Plaq isn't really understood in SjS, and it's a unique classification of drug in treating AIs, there really isn't a substitute for it, but there are other classes of drugs, also called DMARDS disease modifying anti-rheumatic drugs that are also used.