If in about 6 to 8 weeks you aren't seeing the slightest change, or don't feel it is enough, let your doc know, and he can adjust. Plaquenil is used to inhibit disease progression - most of us are started on it immediately and need to remain on it long-term. Generally a rheumy will then choose one of these three; Imuran, Cellcept, or MTX to inhibit the over-active autoimmune system that is Lupus. Others here have gotten great results from either Imuran or MTX. I see that in June you were asking about MTX (Methotrexate). I found that following my Dr's instinct/experience/training gave me good results. Chloroquine phosphate eye drops Hydroxychloroquine potassium These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. Plaquenil changes the way your immune system works. In some kinds of lupus, your immune system attacks your body instead of protecting it. Plaquenil tries to quiet or slow down the immune system. Once lupus has been diagnosed, your doctor will develop a treatment plan for you based on your age, sex, health, symptoms, and lifestyle. In developing your treatment plan, your doctor has several goals 1 Reduce inflammation caused by the disease Suppress immune system abnormalities that are responsible for tissue. So my Dr moved on to Cellcept, which was a miracle medication for me. There are no clear guidelines that recommend starting with one of these over the others -- and it's hit-and-miss which one will work best for any individual patient. The Dr knows exactly how your individual manifestation of the disease is presenting, what has already been tried, how you reacted to it... She choose Imuran over Methotrexate because I enjoy red wine on the weekends. How does azathioprine work with plaquenil for lupus How is imuran azathioprine used to treat lupus?, Lupus Medicines Hydroxychloroquine - Brigham and Women's. How to come off hydroxychloroquineAralen patient teachingOrder aralen prescribingDoes plaquenil A Botox and Restylane for patient under Lupus medication The risk is not with Botox or Restylane in a patient such as yourself. The risk lies with the medications you are taking Prednisone and Azathioprine -- both these medications are powerful immunosupressants. Is Botox and Restylane Safe for Patient Under Lupus.. Lupus Treatment Options. Lupus remission Lupus Foundation of America. Even though Imuran is effective in treating serious lupus symptoms, long term use of this medication does increase the risk of developing cancer. Your doctor can speak with you about this risk and any other concerns you may have. She/he will work with you to minimize the side effects of your medications while also maximizing the benefits. Azathioprine Imuran is commonly used as a treatment for systemic lupus erythematosus and lupus nephritis. Learn about how it works and its effectiveness. Plaquenil is used to inhibit disease progression - most of us are started on it immediately and need to remain on it long-term. Takes 2-3 months to build up in your system. Generally a rheumy will then choose one of these three; Imuran, Cellcept, or MTX to inhibit the over-active autoimmune system that is Lupus.