Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil meme Hydroxychloroquine effects on kidneys Plaquenil and thyroid Chlortetracycline has been used in livestock agriculture to promote growth through increased food intake, weight gain, and improved herd health 11. Since the 1940s, tetracyclines have been associated with weight gain in human infants and children 12, and one study showed significant weight gain in adults 13. Over all I do feel it may have caused increased anxiety and depression and irritability.however lupus alone can trigger those symptoms I'm sure. Overall Plaquenil did take away the muscle and joint pain. It worked wonders for that. For that reason I am satisfied with plaquenil for what I took it for. Took about 5-6 months to see full effect. Little appetite with plaquenil? lupi1109 posted I started to take plaquenil for my mild lupus about 3 weeks ago and I noticed that I am having less appetite these days. I get hungry during dinner time, but all the foods does not taste as good as before. It feels weird! Eating delicious food was one of the joy of my life. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil increased appetite Plaquenil and unrelenting hunger - Arthritis - Inspire, PLAQUENIL Side Effects, Reviews by Patients - Build up of plaquenil symptomsAct with chloroquine tafenoquineChloroquine phosphate 250 mg day Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Plaquenil Side Effects Common, Severe, Long Term -. Little appetite with plaquenil?" Lupus Community.. Common and Rare Side Effects for Plaquenil Oral. Combining telbivudine Tyzeka and hydroxychloroquine may increase the risk of unexplained muscle pain, tenderness, or weakness because both drugs cause such side effects. Hydroxychloroquine suppresses the immune system and should not be combined with drugs that also suppress the immune system or live vaccines. I started to take plaquenil for my mild lupus about 3 weeks ago and I noticed that I am having less appetite these days. I get hungry during dinner time, but all the foods does not taste as good as before. It feels weird! Eating delicious food was one of the joy of my life. The food that I used to love does not taste as good as before. humm. Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints.