Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take chloroquine with all of your drugs and health problems. Take plaquenil while healing leaky gut Plaquenil muscle weakness Dose equivalence and conversion. Doses expressed as chloroquine base. Each tablet contains 155 mg of chloroquine base equivalent to 250 mg of chloroquine phosphate. Syrup contains 50 mg/5 mL of chloroquine base equivalent to 80 mg/5 mL of chloroquine phosphate. Medscape - Indication-specific dosing for Aralen, Chloroquine phosphate chloroquine, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Chloroquine has a long half-life, which can vary between 74 hours and 50 days, depending on the cumulative dose. The drug can remain in the skin for 6–7 months after the cessation of therapy. Chloroquine dosing. Chloroquine phosphate is dispensed as a 250 mg tablet, which is equivalent to 155 mg chloroquine base. For all uses of chloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Cumulative chloroquine dosage Chloroquine Indications, Side Effects, Warnings -, Aralen, Chloroquine phosphate chloroquine dosing. Stopping and starting plaquenil For Adult Initially 620 mg, then 310 mg after 6–8 hours, then 310 mg daily for 2 days, approximate total cumulative dose of 25 mg/kg of base. https//org.uk/drug/ Fatal dose seems to be from 2.25g upwards so there's a margin but you can kill yourself if you knock back a whole box of tablets 20x250mg usually. Post-exposure Chloroquine Prophylaxis COVID19. Chloroquine DermNet NZ. Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs. Keep chloroquine daily dose at 3 mg/kg/day and cumulative dose at 460 gm to reduce chances of retinopathy ; Keep hydroxychloroquine daily dose at 6.5mg/kg/day and cumulative dose at 1000gm to reduce chances of retinopathy ; Recognize that patients with renal failure are at unusually high risk of retinal toxicity Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been. Provided encouraging results on the safety of a high dosage of the drug up to 500 mg of chloroquine base per day even during pregnancy.