Symptoms of retinal damage from plaquenil

Discussion in 'International Pharmacy' started by denis_s, 02-Mar-2020.

  1. Includer XenForo Moderator

    Symptoms of retinal damage from plaquenil


    She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation.

    Drugs similar to plaquenil Hydroxychloroquine with methotrexate combination

    However, most patients usually notice symptoms only after scotomas have become severe. When allowed to advance, hydroxychloroquine retinal toxicity leads to loss of up to three visual functions acuity, peripheral vision and night vision. Signs. Symptoms. Over time, Plaquenil can accumulate in the retina and cause permanent irreversible damage to the center of vision. The classic retinal changes appear as a “bull’s eye” area of discoloration of the central part of the retina. Symptoms of Plaquenil toxicity are similar to other macular problems and may include Feb 19, 2020 Tell your doctor if you experience serious side effects of Plaquenil including. muscle weakness, twitching, uncontrolled movement, loss of balance or coordination, blurred vision, light sensitivity, seeing halos around lights,

    Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use.

    Symptoms of retinal damage from plaquenil

    Plaquenil Hydroxychloroquine Sulfate - Sanofi, Plaquenil Toxicity Screening - Retina Group of New York

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  7. Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells.

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    While Plaquenil can cause a variety of symptoms, most of them are minor and temporary. The most serious symptom, however, is neither minor nor temporary. Permanent, vision-altering retinal damage has been documented in some long-time users of Plaquenil, but it has been regarded as rare, as long as patients use doses appropriate to their mass. Hydroxychloroquine is an effective and relatively safe drug that can cause retinal toxicity in a minority of patients. Early diagnosis is important to stop treatment and prevent possible further damage. Stopped prior to retinal pigment epithelial damage or bull’s eye maculopathy, retinal findings may remain stable without progression5. In addition, most patients with retinal toxicity have no visual symptoms until severe damage is done. Therefore early screening is essential. New objective screening modalities including spectral domain optical

     
  8. mochalov Guest

    Plaquenil is also known as hydroxychloroquine, so the parent drug Chloroquine can be substituted. Plaquenil hydroxychloroquine Alternatives & Similar. Treating Lupus with Anti-Malarial Drugs Johns Hopkins. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
  9. karlitto Well-Known Member

    CHLOROQUINE PHOSPHATE, USP In animals, from 200 to 700 times the plasma concentration may be found in the liver, spleen, kidney, and lung; leukocytes also concentrate the drug. The brain and spinal cord, in contrast, contain only 10 to 30 times the amount present in plasma. Chloroquine undergoes appreciable degradation in the body.

    Chloroquine Oral Uses, Side Effects, Interactions, Pictures.
     
  10. Jenetellplerm New Member

    The Risk of Retinal Toxicity with Plaquenil One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur.

    Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs.