I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Chloroquine related chloroform Hydroxychloroquine contraindicated in pregnancy Doea plaquenil affect the immune system Plaquenil wrong medication You really should talk to your doctor about your tapering schedule and any side effects you’re experiencing. They may want you to slow down. Plaquenil can take up 1-2 months to start working and up to six months for full effect. More information for Plaquenil can be found here. Have you been prescribed steroid treatment for your RA? The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. How to taper off of plaquenil Stopping plaquenil. DailyStrength, How to taper off of Diphenhydramine - Addiction Substance. Hydroxychloroquine headachePlaquenil e malaria If you've successfully tapered off opioid pain medication in the past, taking opioids for a brief time — with guidance from your doctor — may be appropriate. Discuss all your medication and pain management options, including pros and cons, with your doctor. Let your doctor know whether you had any trouble tapering off opioids in the past. Tapering off opioids When and how - Mayo Clinic. Plaquenil Withdrawal – Life As An Anomaly. Is it common practice to wean off plaquenil.. Have been on methotrexate 20mg email@example.com for about a year and 1/2. Recently moved and have a new Rheumatoligist who did his own blood test and x-rays, according to him he cannot find the blood factor or damage to any joints to prove that I have RA. I would like to know can I stop taking methotrexate or do I have to ween off of it slowly? Or should I even be thinking of stopping the meds? I. You can stop both meds abruptly if that is what you want - there is no need to wean. You should talk to your doctor first though. It is likely you will experience some form of pain and weaning at least your nabumetone may help to deal with this. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory.