The differential diagnosis includes actinic keratoses, sebborheic dermatitis, lupus vulgaris, sarcoidosis, drug rash, Bowen’s disease, lichen planus, tertiary syphilis, polymorphous light eruption, lymphocytic infiltration, psoriasis, and systemic lupus erythematosus. Treatment for discoid lupus erythematosus includes smoking cessation and a sunscreen that protects against both UVA and UVB light as well as very strong topical steroids or steroids injected into the lesions. Complications of chloroquine Psoriasis and hydroxychloroquine Chloroquine protocol for travel Plaquenil steady state These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. Medications commonly used to treat malaria, such as hydroxychloroquine Plaquenil, affect the immune system and can help decrease the risk of lupus flares. Side effects can include stomach upset and, very rarely, damage to the retina of the eye. Hydroxychloroquine is used for its effect on systemic lupus erythematosus SLE disease activity and long-term benefits. This can be limited by adherence. One way to assess adherence is to measure blood levels. Conflicting data exist regarding blood levels. If a patient does not have any signs of systemic lupus erythematosus, such as generalized hair loss, ulcers in the mouth or nose, Raynaud's phenomenon, arthritis, or fever at the time that he develops discoid lupus, he will most likely only have discoid lupus and will never develop systemic lupus erythematosus. Other oral medications used to treat discoid lupus include retinoids (isotretinoin or acitretin), dapsone, thalidomide (teratogenic, side effects include peripheral neuropathy), azathioprine, methotrexate, or gold. Plaquenil discoid lupus Plaquenil User Reviews for Systemic Lupus. -, Lupus - Diagnosis and treatment - Mayo Clinic Hydroxychloroquine dose in sleChloroquine maculopathy cumulative dose Losing Hair on Plaquenil The 5 Possibilities. Hydroxychloroquine also known by its popular brand name Plaquenil is an oral medication that is commonly used to treat a variety of autoimmune diseases including systemic lupus, dermatomyositis, rheumatoid arthritis, Sjogren’s and many other conditions as well. Hydroxychloroquine Plaquenil and Hair Loss Is my Plaquenil.. Hydroxychloroquine Blood Levels in SLE Clarifying dosing.. Lupus-Specific Skin Disease and Skin Problems Johns Hopkins Lupus Center. Discoid lupus erythematosus DLE is a chronic photosensitive skin eruption which can be either localised or widespread. It is confined to the skin and does not cause any systemic symptoms. Discoid Lupus. Lupus is a widespread and chronic lifelong autoimmune disease that, for unknown reasons, causes the immune system to attack the body’s own tissue and organs, including the joints, kidneys, heart, lungs, brain, blood, or skin. Plaquenil is also indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults, and for the treatment of acute and chronic rheumatoid arthritis in adults. • Postmarketing cases of life-threatening and fatal cardiomyopathy have been reported with use of Plaquenil and chloroquine.