Please review the following URL and make sure that it is spelled correctly. Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). What does plaquenil do to your eyes Plaquenil for oral lichen planus Use of chloroquine during pregnancy Plaquenil itself probably does not have a direct affect on your immune system - it is a DMARD and is not considered to be an immunosuppressant. However, many with active autoimmune diseases feel that they are not succeptible to many of the common viruses that they are exposed to - somewhat of a silver lining. I doubt it is the Plaquenil affecting your immune system, but the actual Lupus itself as it can affects the white blood cells and lower them so we get every infection going. You need to speak to your rheumy for more clarification in your case. A comprehensive guide to side effects including common and rare side effects when taking Plaquenil Hydroxychloroquine includes uses, warnings, and drug interactions. Drugs A-Z Pill Identifier Supplements Symptom Checker Diseases Dictionary Media;. Immune system disorders Urticaria, angioedema, bronchospasm. It may prevent joint damage and reduce the risk of long-term disability. It can decrease the pain and swelling of arthritis. Plaquenil immune system Do either hydroxychol/Plaquenil put you at risk for greater., Plaquenil and immune system Lupus Forums at The Lupus Site Chloroquine in vivoWhat is chloroquine made up ofWhat symptoms does plaquenil treat There is evidence that hydroxychloroquine may interfere with communication between cells in the immune system. This action suppresses the normally overactive immune response in lupus patients which may explain one reason Plaquenil works so well for those suffering with lupus. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. PATIENT FACT SHEET Hydroxychloroquine Plaquenil. Any one have any experience or info regarding pre-existing precancerous conditions and the effects of Plaquenil on the immune system. I see so much info on the net where some says that Plaquenil has very mild effect on immune system except for eye issues --- Other info says it is an immunosuppressant. Medications that Weaken Your Immune System and Fungal Infections. Related Pages. Overall, most serious fungal infections are rare, but they do happen. They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory.