Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine hyperpigmentation pictures face Plaquenil aps pregnancy Common side effects include allergy to the medication, GI disturbances such as nausea or diarrhea, and changes of pigmentation in the skin or hair this is not a complete list. You should also be tested for an enzyme called g6pd before starting, and you should have at least one eye exam annually while on the drug. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Although they are uncommon, Plaquenil has side effects that may affect your eyes. Plaquenil and Your Eyes In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Most common side effects of plaquenil Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Does plaquenil cause macular degenerationSjogrens and plaquenil Many doctors disagree about the effects of plaquenil on the arthritis. It does help in about 60 % of the cases of arthritis by significantly reducing the pain. However, about 20 – 30 percent of people stop using it because of the side effects. Side effects include digestive problems, skin rash and disorders of skin pigmentation. Side effects of Plaquenil Other Drugs discussions.. Plaquenil Side Effects on Your Eyes and Vision. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Plaquenil side effects over time. applicable Plaquenil side effects by gender. Plaquenil side effects by age. Drug Information on Plaquenil, Plaquenil Sulfate, Quineprox hydroxychloroquine includes side effects, uses, drug interactions, dosage, drug pictures, overdose symptoms, and what to avoid. Topics A-Z Slideshows Images Quizzes Supplements Medications Among those who do, common side effects include nausea, stomach cramps, dizziness, headaches, and diarrhea. These side effects often decrease over time. Plaquenil can cause serious eye problems, especially if taken at high doses or for longer than five years.